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<  Voorstellen  ~  General Knowledge of Enfuvirtide Acetate

xysoom
Geplaatst: Wo-Sep-2019 08:04:48 Reageren met citaat
Geregistreerd op: 21 Jul 2019 Berichten: 195
General Knowledge of Enfuvirtide Acetate




Enfuvirtide powder works by disrupting the HIV-1 molecular machinery at the final stage of fusion with the target cell, preventing uninfected cells from becoming infected. A biomimetic peptide, enfuvirtide was designed to mimic components of the HIV-1 fusion machinery and displace them, preventing normal fusion. Drugs that disrupt fusion of virus and target cell are termed entry inhibitors or fusion inhibitors.
HIV binds to the host CD4+ cell receptor via the viral protein gp120; gp41, a viral transmembrane protein, then undergoes a conformational change that assists in the fusion of the viral membrane to the host cell membrane. Enfuvirtide binds to gp41 preventing the creation of an entry pore for the capsid of the virus, keeping it out of the cell.
Enfuvirtide acetate is a kind of white powder
Molecular Formula: C204H301N51O64
CAS No.: 159519-65-0
Description of Enfuvirtide Acetate:
Water Content(Karl Fischer) :≤5.0%
Acetate Content(by HPLC) :≤10.0%
Amino Acid Composition: ±15% of theoretical
Purity (by HPLC) :≥95.0%
Single Impurity(by HPLC) :≤2.0%
Peptide Content(by %N) :≥80%
Assay (By Anhydrous, Acetic Acid-free ) :95.0~105.0%
Bacterial Endotoxins :≤5EU/mg
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SkyeLittle
Geplaatst: Di-Dec-2020 02:26:04 Reageren met citaat
Geregistreerd op: 07 Dec 2020 Berichten: 1
Asking questions on message boards is good as people generally reply quickly. I am in favor of using a message board site but asking a machinery question is what seems strange to me as it's rather a practice question not theory. Let's hope you get your answer quickly.
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